Drug information of Alprazolam


Drug group:

Alprazolam belongs to a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). It works by slowing down the movement of chemicals in the brain that may become unbalanced. This results in a reduction in nervous tension (anxiety). Alprazolam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Mechanism of effect

CNS agents of the 1,4 benzodiazepine class presumably exert their effects by binding at stereo specific receptors at several sites within the central nervous system. Their exact mechanism of action is unknown. Clinically, all benzodiazepines cause a dose-related central nervous system depressant activity varying from mild impairment of task performance to hypnosis.


Alprazolam, a benzodiazepine, is used to treat panic disorder and anxiety disorder.


Alprazolam, a benzodiazepine, is used to treat panic disorder and anxiety disorder. P: Following oral administration, Alprazolam is readily absorbed. Peak concentrations in the plasma occur in 1 to 2 hours following administration. In vitro, Alprazolam is bound (80 percent) to human serum protein. Alprazolam and its metabolites are excreted primarily in the urine.

Drug indications

Depression , Anxiety , Panic Disorder


Usual Adult Dose for Anxiety Immediate-release tablets, orally disintegrating tablets, oral concentrate: Initial dose: 0.25 to 0.5 mg orally 3 times a day This dose may be gradually increased every 3 to 4 days if needed and tolerated. Maintenance dose: May increase up to maximum daily dose of 4 mg in divided doses


1-Dependence and Withdrawal Reactions, Including Seizures may occure. 2-Withdrawal reactions may occur when dosage reduction occurs for any reason. This includes purposeful tapering, but also inadvertent reduction of dose (eg, the patient forgets, the patient is admitted to a hospital). Therefore, the dosage of Alprazolam tablets should be reduced or discontinued gradually. 3-Because of its CNS depressant effects, patients receiving Alprazolam tablets should be cautioned against engaging in hazardous occupations or activities requiring complete mental alertness such as operating machinery or driving a motor vehicle. 4-patients should be cautioned about the simultaneous ingestion of alcohol and other CNS depressant drugs during treatment with Alprazolam tablets.

Points of recommendation

1-Not recommended for use in pregnancy. 2-Do not increase the dose even if you think the medication "does not work anymore" without consulting your physician. 3-Do not stop taking this medication abruptly or decrease the dose without consulting your physician, since withdrawal symptoms can occur.

Pregnancy level


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