Piracetam
In the United States, it is not approved by the US Food and Drug Administration for any medical use and it is not permitted to be sold as a dietary supplement. In the UK, piracetam is prescribed mainly for myoclonus, but is used off-label for other conditions. Evidence to support its use for many conditions is unclear.
Mechanism of effect
Piracetam improves the functioning of the (ACh) transmitters and receptors. Acetylcholine, abbreviated as (ACh), is implicated in memory processes and development. Choline sources, like Alpha GPC and choline bitartrate, increase the production of Acetylcholine. Piracetam, belonging to the racetam class of nootropics, stimulates, increases, and improves the activities of these ACh receptors
Pharmacodynamic
Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid. Piracetam is a cyclic derivative of GABA.
Drug indications
Dosage
The standard piracetam dose for children is between 40-100mg per kilogram of bodyweight. This dose is intended for the treatment of breath-holding spells, though it has also been used for children with dyslexia. The lower end of the range (40-50mg/kg) is used most often. The standard piracetam dose for adults is between 1,200-4,800mg a day. The largest effective dose is 1,600mg, taken three times a day for a total of 4,800mg.
Drug contraindications
Pregnancy , Lactation , hypersensitivity to drug or its components. , Severe Renal Impairment , severe hepatic impairment
Side effects
insomnia , fatigue , hpyerkinesia
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