Drug information of Glutathione


Drug group:

Male infertility (IM use), atherosclerosis (IV, PO use), cancers, chemotherapy adjunct (IM, IV use), diabetes (IV use), immunostimulant, liver diseases, lung diseases (inhaled use), memory loss, Parkinson's disease (IV, PO use)

Mechanism of effect

It is a powerful antioxidant, co-factor in Phase I hepatic detoxification, involved in synthesis of DNA & proteins, amino acid transport, enzyme activation, immune system function
It is a tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides


Not Available


Research suggests that glutathione is not orally bioactive, and that very little
of oral glutathione tablets or capsules is actually absorbed by the body

:Volume of distribution
Not Available

Not Available

:Route of elimination
Not Available

Not Available

Not Available


Chemotherapy adjunct
600mg/day IM days 2-5 of chemotherapy
1.5g/m² IV before chemotherapy

Male Infertility
600mg IM QOD x 2 months

250mg PO QD
dosage range: 50-600mg/day

600mg NEB BID

Points of recommendation

:Probable adverse reactions
allergic reaction, like rash, hives, itching, red, swollen, blistered, or peeling skin with or without fever, wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat, dizziness or passing out

Asthma (inhaled use)

:Drug or Food Interactions
Not Available

Pregnancy level

Avoid use

Breast feeding warning

Avoid use

Related drugs

Acethyl cysteine

Ask a Pharmacist

User's questions
    No comments yet.