moxisylyte
This medicine is not intended for children under 18 years.
moxisylte is used for the short-term control of Raynaud’s Phenomenon in adults. This is a condition where the fingers and toes become discoloured and is triggered by responses to cold, or emotional distress. Opilon helps by improving blood circulation to the extremities.
Mechanism of effect
Moxisylyte is vasodilator that works as a specific alpha-adrenergic blocking agent. Its action is known to be competitive against norepinephrine without beta-receptor blocking, anti-angiotensin or anti-serotonin activity
Pharmacodynamic
Administration of moxisylyte has shown to improve peripheral flow in occlusive arterial disease with little effect in blood pressure. There are reports of increases in cutaneous blood flow and skin temperature after local application of moxisylyte
Pharmacokinetics
Moxisylyte is rapidly absorbed after oral administration
In preclinical trials, the volume of distribution presented for beagle dogs is in the range of 0.83-0.98 L/kg
The pharmacokinetic profile of moxisylyte can make this drug to be considered as a prodrug as its biotransformation is very rapid
Drug contraindications
Opilon tablets are contraindicated in those with a hypersensitivity to any of the ingredients or who have active liver disease.
Side effects
Stop taking Opilon and seek immediate medical attention if you experience the following: jaundice (yellowing of the skin and eyes). This side effect is rare and may indicate that the medicine has affected your liver. Other side effects that have been reported are: mild nausea (feeling sick) diarrhoea headache flushing of the face giddiness (a feeling of dizziness or spinning) rash
Alerts
Talk to your doctor or pharmacist before taking Opilon if any of the following applies to you:
diabetes
high blood pressure
taking tricyclic antidepressants
are over 65 years of age
Points of recommendation
This medicine is not intended for children under 18 years.
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. The recommended dose varies from person to person and depends on your condition. Your doctor will tell you how many tablets to take and for how long you should take them. Swallow the tablets whole with some water. Try to take the tablets at the same time every day. If there is no improvement within two weeks of starting Opilon, your doctor will probably stop your treatment
Pregnancy level
is not recommended for use if you are pregnant, think you might be pregnant or are planning to become pregnant, as its safety has not been established.
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