Drug information of Miconazole


Miconazole

Drug group:

Miconazole is an antifungal medication that fights infections caused by fungus. Miconazole buccal is used to treat candida (yeast) infections inside the mouth.

Mechanism of effect

Inhibits biosynthesis of ergosterol, damaging the fungal cell wall membrane, which increases permeability causing leaking of nutrients

Pharmacodynamic

Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral),

Pharmacokinetics

Absorption:Minimal Duration of Action:Buccal adhesion: 15 hours

Drug indications

fungal infections

Dosage

Dosing: Adult Oropharyngeal candidiasis: Buccal tablet: 50 mg (1 tablet) applied to the upper gum region once daily for 14 days

Alerts

1- Although systemic absorption is typically minimal, use with caution in patients with hepatic impairment. 2-Monitor patients with a history of azole hypersensitivity.

Points of recommendation

Miconazole should be discontinued at once at the first sign of hypersensitivity.

Pregnancy level

C


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