Drug information of Calamine


Drug group:

Calamine topical (for the skin) is used to treat itching and skin irritation caused by chickenpox, insect bites or stings, measles, eczema, sunburn, poison ivy, and other minor skin conditions.

Mechanism of effect

Calamine is an anti-itch medicine that works by causing a cooling sensation as it evaporates on your skin. Calamine also dries oozing or weeping from minor skin irritation.

Drug indications



Apply to affected area as often as needed

Side effects

Infection , urticaria , redness , Rash


 For external use only; avoid contact with eyes and mucous membranes. Discontinue use and contact healthcare provider if needed for >7 days or if condition worsens.

Some dosage forms may contain propylene glycol; in neonates large amounts of propylene glycol delivered topically have been associated with potentially fatal toxicities which can include metabolic acidosis, seizures, renal failure, and CNS depression; toxicities have also been reported in children and adults including hyperosmolality, lactic acidosis, seizures and respiratory depression; use caution (AAP 1997; Shehab 2009).

Do not take by mouth. Calamine topical is for use only on the skin. If this medicine gets in your eyes, nose, mouth, rectum, or vagina, rinse with water.

Avoid using other medications on the areas you treat with calamine unless your doctor tells you to.

Points of recommendation

  • Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
  • Before you apply calamine topical, wash the skin with soap and water. Allow the skin to dry completely.
  • Shake the calamine lotion well just before each use.
  • Wash your hands with soap and water after applying the medicine.
  • Call your doctor if your symptoms do not improve after 7 days of treatment, or if your symptoms clear up and then come back.
  • Store at room temperature away from moisture and heat. Do not freeze or refrigerate.

Pregnancy level

Not assigned

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