Drug information of Tobramycin ophthalmic

Mechanism of effect

Tobramycin binds irreversibly to one of two aminoglycoside binding sites on the 30 S ribosomal subunit, inhibiting bacterial protein synthesis.

Pharmacodynamic

Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius

Dosage

In mild to moderate disease, instill one or two drops into the affected eye(s) every four hours. In severe infections, instill two drops into the eye(s) hourly until improvement, following which treatment should be reduced prior to discontinuation.

Alerts

1-FOR TOPICAL OPHTHALMIC USE ONLY.
2-If a sensitivity reaction to Tobramycin Ophthalmic Solution 0.3% occurs, discontinue use.
3-Safety and effectiveness in pediatric patients below the age of two months has not been established.

Points of recommendation

Do not touch dropper tip to any surface, as this may contaminate the solution.