Drug information of Propolis


Drug group:

Propolis is a natural resin collected from the buds of conifers and other trees by honeybees. It is used by bees to seal walls and strengthen combs of hives, as well as to embalm dead invaders.

Mechanism of effect

Propolis seems to have activity against bacteria, viruses, and fungi. It might also have anti-inflammatory effects and help skin heal.

Drug indications

diabetes , artirit rhomatoid , herpes simplex , Infection , Acne , Inflammatory Bowel Disease , Psoriasis , swelling

Acne, bowel diseases, cancer, dermatitis, cervitis, diverticulitis, laryngitis, psoriasis, rheumatoid arthritis, aphthous ulcers, burns, wound healing, Legg-Calve-Perthes disease, infections, diabetes, swelling, cold sores



  • For diabetes: 500 mg of propolis three times per day for 8 weeks. 900 mg of propolis daily for 12 weeks. 400 mg of propolis daily for 6 months.
  • For swelling (inflammation) and sores inside the mouth (oral mucositis): 80 mg of propolis 2-3 times daily has been used along with rinsing with bicarbonate solution.


  • For cold sores (herpes labialis): Creams or ointments containing propolis 0.5% or 3% applied to the lips 5 times per day at the start of cold sore symptoms.


•For swelling (inflammation) and sores inside the mouth : 5 mL of propolis 30% mouth rinse for 60 seconds three times daily for 7 days has been used.  Propolis 2% to 3%  has been applied to dentures 3-4 times daily for 7-14 daily.

Drug contraindications

Hypersensitivity to bee products

Side effects

allergic reactions

-Allergic reactions with skin and mucous membrane irritations have been reported. Sensitization to propolis also has been reported.

-Some experts believe certain chemicals in propolis may make asthma worse.

-A certain chemical in propolis might slow blood clotting


no information for PROPOLIS Interactions


-Some people are allergic

-There is not enough reliable information about the safety of taking propolis if you are pregnant or breast-feeding. Stay on the safe side and avoid useTaking propolis might increase the risk of bleeding in people with bleeding disorders.

-Avoid using propolis if you have asthma

Points of recommendation

-Taking propolis might increase the risk of bleeding during and after surgery. Stop taking propolis 2 weeks before surgery.

Pregnancy level


Information not available

Breast feeding warning

Information not available

Drug forms

bee glue, bee putty, bienenharz, cera alba, galangin, hive dross, Nivcrisol, propolin H

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