Drug information of Addamel

Mechanism of effect

Addamel N is indicated in patients as a supplement in intravenous nutrition to meet basal to moderately increased requirements of trace elements

Pharmacodynamic

Addamel N is a mixture of trace elements in amounts normally absorbed from the oral diet and should have no pharmacodynamic effect besides maintaining or repleting the nutritional status.

Pharmacokinetics

When infused intravenously, the trace elements in Addamel N are handled in a similar way to trace elements from an oral diet. Individual trace elements will be taken up by tissues to different extents,

Dosage

The recommended daily dosage of Addamel N in adult patients with basal to moderately increased requirements is 10 ml (one ampoule). For children weighing 15 kg or more, the recommended dosage is 0.1 ml Addamel N/kg body weight/day.

Alerts

Addamel N should be used with caution in patients with impaired biliary and/or renal function in whom the excretion of trace elements may be significantly decreased. Addamel N should also be used with caution in patients with biochemical or clinical evidence of liver dysfunction (especially cholestasis). If the treatment is continued for more than 4 weeks, checking of manganese levels is required. Addamel N must not be given undiluted.

Points of recommendation

Addamel N must not be given undiluted

Related drugs

Folic acid , Vitamin H , Vitamin B1 , Vitamin B12 , Vitamin B2 , Vitamin B6 , Iron , Calcium pantothenate